Polynucleotide treatment is a prime example of biostimulation therapy, designed to accelerate the skin’s natural regeneration process. When polynucleotides are injected into the skin, they stimulate fibroblast cells to produce new collagen and elastin, enhancing skin firmness, elasticity, and overall quality.
Polynucleotide treatment is suitable for people over 18 years of age. There is no upper age limit. Those aged between 30 and 40 who want to get rid of signs of fatigue and the first signs of age are the most likely to benefit.
The treatment is particularly suitable for revitalising the thin skin under the eyes and on the neck. Problems with the scalp - such as hair loss - may also be resolved with a polynucleotide treatment series.
Fish DNA has been used as the raw material for the polynucleotide solution, and in America the procedure is affectionately known as "Salmon sperm facial".
Fish allergy is an absolute contraindication to treatment.
Rejuran i for under-eye circles (1 ml)
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Polynucleotides are fragments of DNA or RNA that can be used in biostimulation therapies. Ebeling Beauty's polynucleotide treatments are performed with the CE-approved Rejuran product, which is based on salmon DNA. When injected into the skin, the fish DNA fragments promote the regeneration of collagen and elastin.
Polynucleotide treatments are suitable for people over 18; there is no upper age limit for biostimulation treatments that improve the condition and appearance of the skin.
Above all, this treatment is suitable for people aged between 30 and 40 who want to maintain a youthful, fresh appearance even during their peak years. The treatment does for the skin what the most expensive skincare products in the world promise to do: plump and plump the skin, smooth out features, brighten the under-eye area, smooth out superficial wrinkles.
Polynucleotide treatment can be applied to almost any area of the skin. The DNA fragments in Rejuran are derived from salmon and therefore fish allergy is an absolute contraindication to the treatment.
The most popular treatment areas:
Collagen and elastin are the skin's own proteins, and their levels start to decline around the age of 25. Their decline is mainly reflected in sagging and wrinkling of the skin. Polynucleotides (PN) stimulate the skin's fibroblasts to produce new collagen and elastin. Collagen and elastin synthesis gradually begins to take off over the weeks following treatment. Collagen and elastin re-production is reflected in the skin in several ways:
PN treatment is a new generation of biorevitalisation treatment. The skinbooster hyaluronic acid gels used in classic biorevitalisation treatments provide immediate results such as hydration and light plumping. The DNA derivatives of polynucleotides go further: they activate skin fibroblast cells to a degree more effectively than classic skin boosters. PN molecules reduce inflammation, irritation and redness, increase skin elasticity and rejuvenate its appearance. PN treatment leaves skin looking fresh and renewed.
The treatment strengthens weakened collagen fibres and stimulates dermal fibroblast cells to produce new collagen. The skin's strong collagen network is visible externally in the firmness and clarity of the features.
The treatment also corrects scars, pigmentation changes and sun damage.
As with all biostimulation treatments, the PN treatment is an effective way to deeply hydrate the skin.
Rejuran polynucleotide therapy was developed in South Korea and has been a trusted treatment there for over a decade. To date, more than 10 million syringes have been used in South Korea alone.
Injections are not pampering treatments, as needle pricks always cause some level of discomfort. However, the pain can be minimized with the use of a numbing cream, making the procedure more comfortable.
If you want a cream anesthetic, you have two options:
When booking your appointment, please inform us if you would like to use Ebeling Beauty Anaesthesia. This ensures that we can allocate enough time for the application of the anesthetic cream.
The number of treatments varies. The condition of the client's skin and the goals set for the treatment are decisive.
PN treatment is usually given 2-3 times every 3-4 weeks.
The best treatment path for your skin or scalp will be identified during your free consultation.
The first, albeit modest, results are visible immediately after the end of treatment. However, the best results - and the best results can be assessed - are only seen 2-4 weeks after the end of the series treatment.
Treatment results last well for an average of 6-12 months.
It is recommended to seek maintenance treatment if the results fade. Maintenance treatments are an effective way to keep the skin's ageing processes in check.
The mechanism of action of polynucleotides is different from that of fillers. The filler thickens the thin skin under the eye: it smoothes out the dark circles and the tear through running from the inner corner of the eye towards the cheek.
Polynucleotides by themselves do not fill or saturate anything. They activate the skin's own regeneration processes. As the skin heals, deep moisturises and firms, the effect is visible as a lightening, smoothing and light plumping of the under-eye area.
Polynucleotide treatment is suitable for fading bags under the eyes; filler treatment should not be used on bags under the eyes to prevent the bags from getting worse.
For the best treatment for your under-eye circles, a free consultation is available.
Polynucleotide treatment can prevent, slow and even stop hair loss.
When administered around the hair follicles, PN molecules accelerate blood circulation to the scalp. The blood carries more nutrients to the hair follicles, the lack of which may have caused hair thinning and shedding.
Like all treatments that slow down hair loss, polynucleotide treatments should be started too early rather than too late.
No injection treatment will restore hair to areas that have gone completely bald.
Only substances classified as a medicinal product or medical device may be injected into the skin. Injection of cosmetic solutions into the skin is prohibited.
Rejuran polynucleotide products are thoroughly tested, safe, and CE-marked medical devices. They are available exclusively to healthcare professionals who have been specifically trained in polynucleotide treatments.
The FDA (Food and Drug Administration) is the authority responsible for regulating medicines and medical devices in the US. While FDA approval doesn’t carry legal weight in Europe, it’s still highly respected here because the FDA’s standards are stricter than those required for CE approval. Currently, Rejuran gels are FDA-approved for microneedling polynucleotide treatments. The FDA approval process for Rejuran injections is still underway.
The treatment is suitable for many but not for all.
Contra-indications:
After polynucleotide treatment, the following side effects are normal and possible:
If you have ever suffered from cold sore, PN treatment can provoke a recurrence. It is advisable to take a prophylactic before the procedure.
After your PN treatment, you will receive detailed written aftercare instructions. Follow them carefully. If the instructions differ from the general guidelines below, always adhere to the ones provided by the clinic.
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