Fillers can sometimes be dissolved with a needle, but in most cases, hyaluronidase is used. This enzyme breaks down hyaluronic acid and is available in pharmacies as a compassionate drug.
We offer filler removal services in Kalasatama and Tikkurila, Helsinki.
The hyaluronic acid-based filler can be removed.
Filler removal is usually performed with hyaluronidase, an enzyme that dissolves hyaluronic acid.
Hyaluronidase is naturally present in the human body.
Hyaluronidase, which is available from pharmacies, is a specially authorised product and should always be used by a surgeon, doctor or dentist.
The first effects of hyaluronidase are visible immediately after treatment. The effect continues for some time after the treatment, and the result can only be reliably assessed a few weeks after the procedure.
If a new filler treatment is to be applied to the removal area, a recovery period of at least one month should be allowed between removal and refilling.
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Fillers are usually dissolved using hyaluronidase, an enzyme that breaks down hyaluronic acid. In Finland, it is available under the trade name Hylase. This is a prescription-only medication and requires special authorization.
The number of treatments with fillers has been increasing since the mid-2000s. With the increase in filler treatments, there has also been an increase in failures and even complications of varying degrees. As a result of failed filler treatments, filler removal is nowadays a much sought-after procedure.
Filler removal may be necessary due to filler migration, an unsatisfactory aesthetic result, or a client’s desire to restore their natural lip shape or facial contours. It is typically performed using hyaluronidase, an enzyme that dissolves hyaluronic acid.
In some situations, lip fillers can be removed with a needle alone. However, this is only possible when the filler has formed a clear, relatively superficial and well-defined capsule that can be opened and the contents easily squeezed out.
In some rare cases, surgical removal of the filler may be necessary.
Hyaluronidase breaks down hyaluronic acid
Hyaluronidase is an enzyme that breaks down hyaluronic acid. It is naturally present in the human body. The body's own hyaluronidase breaks down both the body's own hyaluronic acid and synthetic hyaluronic acid gels injected into the skin.
The body's own hyaluronic acid breaks down and is replaced by new hyaluronic acid in 12-24 hour cycles; hyaluronidase can break it down very quickly. Synthetic fillers, on the other hand, take several months to be broken down by the body's own hyaluronidase. This is because hyaluronic acid fillers injected into the skin are rigid gels. The more rigid and solid the filler, the longer it takes the body's own hyaluronidase to break down the filler.
If hyaluronic acid in the filler is to be degraded and removed quickly, laboratory-formulated hyaluronidase is used. When a large enough amount of hyaluronidase is injected into the filler, the filler will break down faster than normal, often within a few days, sometimes even a few hours. The degradation and elimination process starts immediately after hyaluronidase treatment.
How quickly hyaluronidase can break down filler depends on a number of factors:
Because the properties of the filler injected into the skin affect its rate of degradation, the results of a single removal cannot always be accurately predicted. In many cases - but not always - the filler can be removed in a single treatment.
The procedure for removing filler is quick and simple. The treatment area is examined and anaesthetised, then hyaluronidase is injected into the area. Typical after-effects of the treatment include redness, tingling, pain and bruising. The use of an anaesthetic can sometimes increase the after-effects. For most clients, a single removal of the filler is sufficient. However, it is wise to be prepared for two or sometimes more treatments, especially if the area to be removed has undergone several filler treatments or if the filler has spread.
The final result of hyaluronidase treatment is only visible after two weeks of treatment, and if too much is administered the first time, the skin's own hyaluronic acid may also be broken down in the treatment area. Therefore, careful dosing twice is better than overdosing in one injection. If a new filler treatment is to be applied to the removal area, a recovery period of at least one month should be allowed between removal and refilling.
Dissolving fillers are made with hyaluronidase. It is a specially authorised product that can only be used by doctors and dentists or by a healthcare professional working under the actual supervision of a doctor/dentist.
Hyaluronidase is an enzyme produced by white blood cells in the human body. Hyaluronidase enzymes have been found in insects, mammalian tissues and even snake venom. In humans, there are five functional hyaluronidases: HYAL1, HYAL2, HYAL3, HYAL4, HYAL5 and the pseudogel HYAL6. In most tissues, HYAL1 and HYAL2 are the main hyaluronidases.
Hyaluronidase can also be synthesised in the laboratory. Hyaluronidase, available from pharmacies under special authorisation, is used, for example, to increase the absorption of a drug into the tissue. In aesthetic medicine, hyaluronidase is used to remove hyaluronic acid-based fillers.
In filler removal, hyaluronidase is injected into the skin/subcutaneous layer to break down the hyaluronic acid deposit. The hyaluronidase enzyme acts as the opposite of a hyaluronic acid gel, breaking down the hyaluronic acid previously injected into the area. After treatment, you can resume your normal activities. Possible side effects may include swelling, bruising and tenderness of the injection sites. All side effects will disappear on their own within a week of treatment. The first results of the treatment are usually visible after 48 hours. For many patients, a single filler removal is sufficient, but some may need a second or third hyaluronidase treatment. The results of the treatment can be examined at the earliest two weeks after the treatment. Some patients may have to wait three or four weeks for the final result.
A check-up can be scheduled, for example, a month after the removal of the filler. The check-up can assess whether any further treatment is needed.
Side effects of hyaluronidase are rare.
Hyaluronidase injected into the skin is also able to break down the skin's own hyaluronic acid. However, the effect of hyaluronidase is always localised, primarily on the cross-linkages of the gel-like hyaluronic acid and only secondarily on the skin's own liquid hyaluronic acid. It is also worth remembering that even if the hyaluronidase used to remove the filler dissolves your skin's own hyaluronic acid, your body can restore your natural hyaluronic acid reserves to their previous levels in a short time.
In any case, it is important to dose hyaluronidase accurately and sparingly enough to ensure that the skin's own hyaluronic acid is used as little as possible. It is often better to use too little rather than too much hyaluronidase.
Dissolving fillers with hyaluronidase does not break down fat or break down tissue. Hyaluronidase only and only breaks down hyaluronic acid.
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